What is GHRP-2?
GHRP-2 is considered one of the mildest GHRP’s next in line to Ipamorelin. GHRP-2 is a hexapeptide and a pure growth hormone secretagogue. It is also a synthetic agonist of the hormone Ghrelin.
Molecular Mass: 817.9749 g/mol
Molecular Formula: C45H55N9O6
Molecular Sequence: H-D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2
GHRP-2 Benefits
  • Decrease in body fat
  • Increase in lean body mass
  • Promotes faster healing of wounds and injuries
  • Improved the quality of sleep
  • Decreases wrinkling of the skin and improves the elasticity of the skin
  • Increase in bone density
  • Increase in cellular repair
  • Protects and strengthens the heart
  • Increased libido Improves the body’s ability to ward off illness and disease
GHRP-2 Peptide – How does it work?
GHRP-2 is a growth hormone releasing peptide and is a single polypeptide chain composed of six amino acids. A hexapeptide, GHRP-2 stimulates ghrelin release and works to correct deficiencies in growth hormone. Since GHRP-2 is a ghrelin agonist, it helps influence HGH secretion in two ways. For one, it acts to boost GH levels by amplifying the transduction pathway. It also suppresses the action of a hormone called somatostatin which blocks growth hormone release. These activities make GHRP-2 a perfect option from which one can increase growth hormone levels.
The discovery of GHRP’s – What is a GHRP?
GHRP is short for “Growth hormone releasing peptides”. These are a family of peptides acting upon the hypothalamus and the pituitary gland. They release growth hormones through the activation of a particular protein receptor. First identified two decades ago, GHRP’s are a synthetic tissue made up from amino compounds. GHRPs have no structural similarity with one’s natural or endogenous growth hormone-releasing hormone aka GHRH.
Effects of GHRP- 2
  • Increases protein synthesis
  • Stimulates the hypothalamic area of the brain
  • Promotes lipolysis
  • Increases IGF-1 Production
  • Increases calcium retention and bone mineralisation.
  • Promotes glucogenesis in the liver and decreases glucose uptake in the liver
  • Contributes to the functional optimization of the Islet of Langerhans or pancreatic islets.
  • Treats growth hormone deficiency.
GHRP-2 Side effects
The most significant side effect experienced by patients using GHRP-2 is tied to increased hunger, but do note that this increase in appetite is minimal. It does still offer the benefits of ghrelin activation. Ghrelin’s importance is in the fact that it is a regulator of GH secretion and it is one that is produced within the stomach, influenced greatly by the patient’s diet and nutrient quota. Clinical studies have linked an increase of ghrelin to fasting and one’s anticipation of meals. With GHRP-6 this is why the hunger experienced can be considered somewhat extreme, for the peptide can mimic ghrelin effects. With GHRP-2, this side effect has been reduced by chemists, so that the hunger is not as severe. Patients should be aware that GHRP-2 does elevate cortisol and prolactin – particularly if a patient is dosing within the higher ranges of over 200mcg. Another side effect that is common among users starting out on GHRP-2 is a feeling of lethargy.
Other side effects of GHRP-2

  • Elevates Cortisol and Prolactin
  • Feeling Tired or Lethargic upon onset of GHRP-2 use
  • Water retention
  • Tingling and numbness
  • Decreased insulin sensitivity
GHRP-2 Clinical studies and research
  • Laferrère B, Abraham C, Russell CD, Bowers CY. Growth Hormone Releasing Peptide -2 (GHRP-2), like ghrelin, increases food intake in healthy men. The Journal of clinical endocrinology and metabolism. 2005;90(2):611-614. doi:10.1210/jc.2004-1719.
  • Growth hormone secretagogues: mechanism of action and use in aging. Fuh VL1, Bach MA. Growth hormone secretagogues: the clinical future. Micic D1, Casabiell X, Gualillo O, Pombo M, Dieguez C, Casanueva FF.

CJC - 1295 Combination Peptides


CJC - 1295