Symptoms of Premature Ageing

Premature Ageing

Reasons we experience premature ageing.

Ageing, some say, is a natural decline we experience in life that leads to our inevitable exit from this world. We blame memory lapses on our ageing brain and find we suffer more time in recovery after a fall due to our “ageing bones” or lack of muscle mass. But do we know why this occurs? Why do some people age gracefully whilst others seemingly show every new crease and wrinkle. How is it some people are still full of vitality into their 50’s and 60’s, whilst others fall into a cycle of depression, fatigue and weight gain?
Though there are numerous causes for premature aging, there is one reason that often we forget.  It may be that our hormones are imbalanced or on a steady decline.  By approximately 30 years of age, one particular hormone is seen to show significant decline.  (GH) is our most powerful hormone that as children we rely on to grow healthy bones and repair injuries quickly. In adulthood, it facilitates the role of the repair and maintenance hormone, which stimulates tissue repair and replacement when there has been cellular damage or death. At the age of 40, it may surprise you to know that this powerful hormone is often sitting at levels that are half of that of when we were 20. By 60 many people find after having blood tests that they have a clinical GH deficiency.  The less GH produced by our body can potentially reduce our ability to repair damaged cells in a timely fashion. It is this accumulation of unrepaired cell damage that contributes to ageing in some patients. 

Areas of damage due to premature ageing

 
Damage to the skin
The sun’s harmful UV rays, and toxins found in cigarette smoke are all damaging to the skin cells. There are peptides, which promote type II collagen production. Using these peptides under the guidance of a specialist has the potential to reduce wrinkles and create a firmer and more elastic skin.  There are also peptides designed to increase the production of melanin in the skin. This increases skin pigment, producing a tan. An increase in Melanin may potentially buffer some of the damage associated with UV light as opposed to having minimal melanin present in the skin.
Loss of Energy and Sexual Function
In both males and females, often there is a shift in sexual function with ageing. Certain peptides have been shown to increase sex drive and function in men. Many women also report increased sexual desire, as well as heightened pleasure, lubrication and the ability to achieve multiple orgasms.
Bone Deterioration and Fragility
Our bones are supposed to have the strength to support our skeleton, as well as the muscles and ligaments of the body, which help us to perform daily activities. Unfortunately, our bones have been shown to weaken with age. Peptides have been shown to increase bone mineral density and strength. They also have the ability to rejuvenate damaged bone cells. Physicians are aware of peptides and their therapeutic support to bone health and bone disease, and are often prescribed to patients suffering from osteoporosis.
Memory Loss
Aside from occasionally losing your keys or forgetting to pay a bill that was due, there is a much more severe affliction and one that is evidence of chronic degeneration within the brain. Alzheimer’s disease is a disease in which patients experience significant memory loss because their brain cells have been lost or have become dysfunctional. Peptides work to heal brain cells that have been damaged. They promote new nerve cell growth and influence increased connections between the nerve cells. In doing so, this helps with the prevention of age-related cognitive deterioration.

How can anti-ageing peptides help?

Some peptides stimulate our body’s endogenous or “natural” biological production of GH. These peptides are referred to as GH secretagogues. GH is responsible for the repair of cells that have been damaged, stimulating new growth out of dormant stem cells. You can influence your body to repair the damaged cells that are contributing to your symptoms of ageing. This is achieved through the use of GH secretagogue peptides.

In Summary:

Peptides have increased considerably in their appeal as being among the most effective of anti-ageing treatments on the market. Reversing the effects of ageing is achievable through peptide supplementation. Their ability to repair damaged tissue and grow new cells is a regenerative benefit that is hard to ignore. Peptides help maintain health and well-being through their fat loss properties and their ability to facilitate the growth of lean muscle mass.

References

  • Decaroli, M. C., & Rochira, V. (2016). Aging and sex hormones in males. Virulence, 8(5), 545-570.
  • Demontiero, O., Vidal, C., & Duque, G. (2012). Aging and bone loss: new insights for the clinician. Therapeutic advances in musculoskeletal disease, 4(2), 61-76.
  • Chertman, L., Merriam, G., & Kargi, A. (2015). Growth Hormone in Aging. Mdtext.Com, Inc.. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK279163/

  • (2008). Growth hormone and aging: a challenging controversy. Clinical interventions in aging, 3(4), 659-65.
  • Amaro-Ortiz, A., Yan, B., & D’Orazio, J. A. (2014). Ultraviolet radiation, aging and the skin: prevention of damage by topical cAMP manipulation. Molecules (Basel, Switzerland), 19(5), 6202-19. doi:10.3390/molecules19056202
  • Ambler, D. R., Bieber, E. J., & Diamond, M. P. (2012). Sexual function in elderly women: a review of current literature. Reviews in obstetrics & gynecology, 5(1), 16-27.
  • Pfaus, J., Giuliano, F., & Gelez, H. (2018). Bremelanotide: An Overview of Preclinical CNS Effects on Female Sexual Function. The Journal Of Sexual Medicine, 4, 269-279. Retrieved from http://www.academia.edu/17481965/Bremelanotide_an_overview_of_preclinical_CNS_effects_on_female_sexual_function

  • AMAG Pharmaceuticals Announces FDA Acceptance of New Drug Application Filing for Bremelanotide – AMAG Pharmaceuticals. (2018). Amagpharma.com. Retrieved 17 November 2018, from https://www.amagpharma.com/news/amag-pharmaceuticals-announces-fda-acceptance-of-new-drug-application-filing-for-bremelanotide/

  • Liu, J., Saul, D., Böker, K. O., Ernst, J., Lehman, W., & Schilling, A. F. (2018). Current Methods for Skeletal Muscle Tissue Repair and Regeneration. BioMed research international, 2018, 1984879. doi:10.1155/2018/1984879
  • Decaroli, M. C., & Rochira, V. (2016). Aging and sex hormones in males. Virulence, 8(5), 545-570.
  • Demontiero, O., Vidal, C., & Duque, G. (2012). Aging and bone loss: new insights for the clinician. Therapeutic advances in musculoskeletal disease, 4(2), 61-76.
  • Chertman, L., Merriam, G., & Kargi, A. (2015). Growth Hormone in Aging. Mdtext.Com, Inc.. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK279163/

  • (2008). Growth hormone and aging: a challenging controversy. Clinical interventions in aging, 3(4), 659-65.
  • Amaro-Ortiz, A., Yan, B., & D’Orazio, J. A. (2014). Ultraviolet radiation, aging and the skin: prevention of damage by topical cAMP manipulation. Molecules (Basel, Switzerland), 19(5), 6202-19. doi:10.3390/molecules19056202
  • Ambler, D. R., Bieber, E. J., & Diamond, M. P. (2012). Sexual function in elderly women: a review of current literature. Reviews in obstetrics & gynecology, 5(1), 16-27.
  • Pfaus, J., Giuliano, F., & Gelez, H. (2018). Bremelanotide: An Overview of Preclinical CNS Effects on Female Sexual Function. The Journal Of Sexual Medicine, 4, 269-279. Retrieved from http://www.academia.edu/17481965/Bremelanotide_an_overview_of_preclinical_CNS_effects_on_female_sexual_function

  • AMAG Pharmaceuticals Announces FDA Acceptance of New Drug Application Filing for Bremelanotide – AMAG Pharmaceuticals. (2018). Amagpharma.com. Retrieved 17 November 2018, from https://www.amagpharma.com/news/amag-pharmaceuticals-announces-fda-acceptance-of-new-drug-application-filing-for-bremelanotide/

  • Liu, J., Saul, D., Böker, K. O., Ernst, J., Lehman, W., & Schilling, A. F. (2018). Current Methods for Skeletal Muscle Tissue Repair and Regeneration. BioMed research international, 2018, 1984879. doi:10.1155/2018/1984879
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